Living donor liver transplantation in small infants is a significant challenge. Liver allografts from adults may be large in size. This is accompanied by problems of graft perfusion, dysfunction, and the inability to achieve primary closure of the abdomen. Monosegment grafts are a way to address these issues. Monosegment grafts are suitable to use for small infants below 6 kg weight.They allow primary closure of the abdomen in a safe and effective manner. Reduction in situ in the living donor is safe and easily reproducible.
Dr. Vishnu Biradar, Paediatric Gastroenterologist along with an illuminary team of doctors has just published a paper on monosegment grafts in infant liver transplantation cases where mono-segment 2 liver allografts were used successfully.